My Friend’s Little Sister Has It In For Me!
“My Friend’s Little Sister Has It In For Me” The story follows Akiteru, a high school student who’s calm, smart, and a bit too serious. He’s working with his best friend Iroha’s older brother on a secret game development project. But things get messy when Iroha, his best friend’s little sister, starts teasing him nonstop. She’s cute, clever, and always trying to get under his skin. At first, Akiteru thinks she’s just annoying, but over time, he realizes there’s more to her than meets the eye.
As the story goes on, Akiteru gets caught up in web of confusing relationships, hidden feelings, and unexpected challenges. He has to deal with classmates, family expectations, and his own emotions-all while trying to keep the game project on track. The series mixes comedy with emotional depth, showing how people grow through awkward but meaningful experiences.
🧐 Final Thoughts
This series is a great pick for anyone who enjoys romantic comedy with a twist. It’s not just about love-it’s about growing up, dealing with awkward situations, and learning how to connect with others. The story is easy to follow, and the characters feel real even when they’re acting silly. Akiteru’s calm personality clashes with Iroha’s playful teasing, and that makes their interactions fun to watch. You’ll laugh at their misunderstandings, but you’ll also see how they slowly understand each other better.
The anime adds colorful visuals and voice acting that bring the story to life. Whether you’re into light novels or just starting with anime, this series is a good entry point. It’s lighthearted but has moments that make you think about friendship, trust, and growing closer to people. If you like stories that mix humor with heart, this one’s worth your time.

Japanese: 友達の妹が俺にだけウザい
Type: TV
Total Episodes: 12
Statues: Currently Airing
Duration: 23 Min
Aired: Oct-05-2025 to ?-?-?
Season: Fall 2025
Studio: Blade
Demographic: Shounen
Themes: School, Romance
– 🎥 Production Details 🎥 –
- Source Material : Light Novel written by Ghost Mikawa.
- Studio : BLADE
- Director : Kazuomi Koga
- Series Composition : Toko Machida
- Character Design : Katsuyuki Satou
- Music Composer : Not Confirm
- Sound Director : Not yet publicly announced.
- Opening Theme Song : “Uzakawaikute Nani ga warui!” by Karubi Akami
- Ending Theme Song : “Hoshi no Kodou” by Kohana Lam.
– 🎭 Characters & Voice Actors 🎭 –
Ilustración especial protagonizada por Mashiro Tsukinomori e Iroha Kohinata del anime "Tomodachi no Imouto ga Ore ni dake Uzai (My Friend's Little Sister Has It In for Me!), incluida en la revista Newtype edición 11/2025.#友達の妹が俺にだけウザい#いもウザ #imouza pic.twitter.com/nskBXewu0J
— Subarashii Anime (@subarashiiani) October 13, 2025

At least he's honest 😆
— Anime Corner (@animecorner_ac) October 21, 2025
Anime: My Friend's Little Sister Has It In for Me! pic.twitter.com/44eIhoT655
Yeah this definitely give’s “my friends little sister has it in for me” type of vibes, surely that’s not the title of the anime-
— MizuSawa (@EmiIiaSupremacy) October 4, 2025
Oh wait pic.twitter.com/1lcH8DbaBb
Ghost Mikawa is a well known Japanese author and mangaka, who started his career in 2012 after winning the Sliver Award in the 18th Dengeki Novel Grand Prize for his debut work. He’s best known for creating My Friends Little Sister Has It In for Me! and days with My stepsister, both of which have been adapted into manga and anime. Mikawa’s writhing style mixes humor with heartfelt moments and his character often grow through awkward but meaningful interaction. Also if you enjoy slice of life, romantic comedy or stories with a bit of chaos and charm, his work is a great place to start.
🎬 Spotlight
- Fans enjoy the playful, teasing relation ship in his stories.
- Many fans are already into light novel and anime.
- Fans are exited about anime version of his works and often discuss voice actors, animation quality and how well the adaptation capture the original.

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